β‐asarone inhibited cell growth and promoted autophagy via P53/Bcl‐2/Bclin‐1 and P53/AMPK/mTOR pathways in human glioma U251 cells
N Wang, Q Zhang, L Luo, B Ning… - Journal of Cellular …, 2018 - Wiley Online Library
Glioma is the most common type of primary brain tumor and has an undesirable prognosis.
Autophagy plays an important role in cancer therapy, but it is effect is still not definite. P53 is
an important tumor suppressor gene and protein that is closely to autophagy. Our aim was to
study the effect of β‐asarone on inhibiting cell proliferation in human glioma U251 cells and
to detect the effect of the inhibition on autophagy through the P53 signal pathway. For cell
growth, the cells were divided into four groups: the model, β‐asarone, temozolomide (TMZ) …
Autophagy plays an important role in cancer therapy, but it is effect is still not definite. P53 is
an important tumor suppressor gene and protein that is closely to autophagy. Our aim was to
study the effect of β‐asarone on inhibiting cell proliferation in human glioma U251 cells and
to detect the effect of the inhibition on autophagy through the P53 signal pathway. For cell
growth, the cells were divided into four groups: the model, β‐asarone, temozolomide (TMZ) …
β-Asarone inhibited cell growth and promoted autophagy via P53/Bcl-2/Bclin-1 and P53/AMPK/mTOR pathways in human glioma U251 cells.
WNB Wang NanBu, ZQX Zhang QinXin, LLY Luo LaiYu… - 2018 - cabidigitallibrary.org
Glioma is the most common type of primary brain tumor and has an undesirable prognosis.
Autophagy plays an important role in cancer therapy, but it is effect is still not definite. P53 is
an important tumor suppressor gene and protein that is closely to autophagy. Our aim was to
study the effect of β-asarone on inhibiting cell proliferation in human glioma U251 cells and
to detect the effect of the inhibition on autophagy through the P53 signal pathway. For cell
growth, the cells were divided into four groups: the model, β-asarone, temozolomide (TMZ) …
Autophagy plays an important role in cancer therapy, but it is effect is still not definite. P53 is
an important tumor suppressor gene and protein that is closely to autophagy. Our aim was to
study the effect of β-asarone on inhibiting cell proliferation in human glioma U251 cells and
to detect the effect of the inhibition on autophagy through the P53 signal pathway. For cell
growth, the cells were divided into four groups: the model, β-asarone, temozolomide (TMZ) …
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